# EVKEEZA (evinacumab-dgnb) Injection > EVKEEZA is an angiopoietin-like 3 (ANGPTL3) inhibitor indicated along with diet and exercise and other low-density lipoprotein-cholesterol (LDL-C) lowering medicines to lower LDL-C in adults and children, aged 1 year and older with homozygous familial hypercholesterolemia (HoFH). See **Important Safety Information** and full **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** on site. > This site is intended for Patients. For the Healthcare Professionals version of the site please visit https://www.evkeezahcp.com/s/. ## Indication EVKEEZA is an injectable prescription medicine used along with diet and exercise and other low-density lipoprotein-cholesterol (LDL-C) lowering medicines to lower LDL-C in adults and children 1 year of age and older with a type of high cholesterol called homozygous familial hypercholesterolemia (HoFH). It is not known if EVKEEZA is safe and effective in children under 1 year of age. ## IMPORTANT SAFETY INFORMATION **Do not use EVKEEZA** if you are allergic to evinacumab-dgnb or to any of the ingredients in EVKEEZA. **Before receiving EVKEEZA, tell your healthcare provider about all of your medical conditions, including if you:** - are pregnant or plan to become pregnant. EVKEEZA may harm your unborn baby. Tell your healthcare provider if you become pregnant while using EVKEEZA. **People who are able to become pregnant:** - Your healthcare provider may do a pregnancy test before you start treatment with EVKEEZA. - You should use an effective method of birth control during treatment and for at least **5 months** after the last dose of EVKEEZA. Talk with your healthcare provider about birth control methods that you can use during this time. - are breastfeeding or plan to breastfeed. It is not known if EVKEEZA passes into your breast milk. You and your healthcare provider should decide if you will receive EVKEEZA or breastfeed. **Tell your healthcare provider about all the medicines you take,** including prescription and over-the-counter medicines, vitamins, and herbal supplements. **EVKEEZA can cause serious side effects, including:** - **Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis.** Tell your healthcare provider right away if you get any of the following symptoms: swelling (mainly of the lips, tongue or throat which makes it difficult to swallow or breathe), breathing problems or wheezing, feeling dizzy or fainting, rash, hives, and itching. **The most common side effects of EVKEEZA include** symptoms of the common cold, flu-like symptoms, dizziness, runny nose, nausea, and feeling tired or weak. Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all the possible side effects of EVKEEZA. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. **Please see full Prescribing Information, including Patient Information.** ## Important Resources - **[Important Safety Information](https://www.evkeeza.com/s/#isi-55)** - **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** - [For Healthcare Professionals](https://evkeezahcp.com/) ## Additional Information This section act as a guide for navigating the content on https://www.evkeeza.com/s/ based on the page descriptions. * [About homozygous FH (HoFH)](https://www.evkeeza.com/s/about-hofh): Learn about homozygous FH (HoFH), including the signs and symptoms. See **Important Safety Information** and full **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** on site. * [How EVKEEZA® (evinacumab-dgnb) works](https://www.evkeeza.com/s/how-it-works): Learn about EVKEEZA, the first-of-its-kind treatment for people with HoFH aged 1 year or older that is added to traditional cholesterol-lowering treatments, diet, and exercise. See **Important Safety Information** and full **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** on site. * [Study results and safety](https://www.evkeeza.com/s/study-results-safety): EVKEEZA® (evinacumab-dgnb) reduced bad cholesterol by nearly 50% after 6 months in adults and children 5 years and older with HoFH in combination with other LDL-C lowering medications. See **Important Safety Information** and full **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** on site. * [Treatment with EVKEEZA® (evinacumab-dgnb)](https://www.evkeeza.com/s/infusion-overview): EVKEEZA is given once a month by a healthcare provider through an intravenous (IV) line (into the veins) over 60 minutes. See **Important Safety Information** and full **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** on site. * [Connect with the HoFH community](https://www.evkeeza.com/s/connect): Connect with HoFH mentors, sign up for an educational webinar, and watch personal stories. See **Important Safety Information** and full **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** on site. * [Support for starting and staying on EVKEEZA® (evinacumab-dgnb)](https://www.evkeeza.com/s/patient-support): Empowering you with support, from getting started to continuing EVKEEZA. See **Important Safety Information** and full **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** on site. * [EVKEEZA® (evinacumab-dgnb) resources](https://www.evkeeza.com/s/resources): Useful resources to help you along your treatment journey. See **Important Safety Information** and full **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** on site. * [Sign up for EVKEEZA® (evinacumab-dgnb) updates](https://www.evkeeza.com/s/signup): Register to get all the latest news about EVKEEZA and living with HoFH. See **Important Safety Information** and full **[Prescribing Information](https://www.regeneron.com/downloads/evkeeza_pi.pdf)** on site. [Sitemap](https://www.evkeeza.com/s/sitemap.xml)